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The Benefits of Personalized Treatments

 Essay within the Benefits of Personal Medicine

d a way, personal medicine has existed for so long as people have recently been practicing medicine. In fact , Hippocrates, Greek medical doctor and so-called " Father of Traditional western Medicine" who also practiced a lot of 2, five-hundred years ago, was himself a proponent of personalized medicine (Sykiotis et al., 2005). For example , in one of his above 70 performs of tips and theories, Hippocrates wrote about the individuality of disease as well as the necessity of giving " diverse [drugs] in order to patients, intended for the sweet ones will not benefit everybody, nor do the astringent types, nor are all the sufferers able to drink the same issues. " Although Hippocrates evaluated factors just like a person's " constitution, " age, and " physical structure, " and also the time of year, to aid his making decisions when recommending drugs, twenty-first-century personalized remedies is all about DNA. Today, the aim of personalized remedies is to utilize information about someone’s genes, including his or her nucleotide sequence, to create drugs better and more secure. But though scientific and industry experts have already been predicting the arrival of DNA-based personal medicine since at least the eighties and the early days of the Human Genome Project, there are simply a handful of gene-based personalized remedies success stories thus far. Her2/neu and Response to Breast Cancer Treatment

One of these successes is the use of the Her2/neu gene being a predictor of breast cancer patients' responses to a drug referred to as Herceptin. Her2/neu codes for a protein receptor (the Her2 receptor) that plays a crucial role inside the signal transduction pathways affiliated with cell growth and difference. All breast growth cells are coated with Her2 pain, but apparently too much of a good thing can be damaging. Specifically, in about 12-15 to 20% of women with invasive cancer of the breast, the cancer cells more than express Her2 new by as much as 100 times. In other words, these kinds of women include hyperactive Her2/new genes; this kind of causes those to make a lot of Her2...

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